Desert Green Algae and Cyanobacteria for Synthetic Biology

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Synthetic biology is the discipline of designing and then engineering artificial systems using biological components. The field of molecular biology and the ability to read the information encoded in DNA are critical to this technical discipline, which also relies on the principles of engineering, detailed knowledge of cell biology, and an understanding of chemistry. Synthetic … Read moreDesert Green Algae and Cyanobacteria for Synthetic Biology

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Targeting Pyroglutamate Aβ in Alzheimer’s Disease

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Amyloid-beta (Aβ) is a collection of peptide fragments derived from cleavage of amyloid precursor protein (APP). Some of these fragments are toxic to neurons and aggregate forming oligomers and fibrils. These clusters of Aβ form plaques that accumulate in the brains of people with dementia due to Alzheimer’s disease (Figure 1). Preventing the accumulation of … Read moreTargeting Pyroglutamate Aβ in Alzheimer’s Disease

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The Central Role of Mitochondria in Red Blood Cells

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Ferrochelatase in heme biosynthesis Ferrochelatase (FECH) is an enzyme found in mitochondria that adds iron ions (Fe2+) into protoporphyrin to produce heme (Figure 1). This biochemical reaction is critical for cell health.  The process is tightly controlled so that cells produce the amount of heme needed and do not accumulate too much of the heme … Read moreThe Central Role of Mitochondria in Red Blood Cells

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