Worth a Closer Look: April 2019

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As I was selecting the articles related to proteomics and disease, I kept a running list of those that piqued my interest. These range in topic and are not all related to proteomics. Most are related to medicine or human disease. Hopefully, I will have time to take a closer look at them all and … Read more

Therapeutic Applications for Inhibitors and Activators of RANKL/RANK Signaling

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Target tissue type, as well as a patient’s gender, nutritional, and reproductive status, must be considered to manipulate signaling through the RANKL/RANK pathway for therapeutic benefit. In some contexts, activating this pathway can be beneficial and in others inhibiting this pathway is beneficial. RANKL is the ligand, RANK [receptor activator of nuclear factor kappa-B (NF-κB)] … Read more