Progress in Lyme Disease Vaccine Development

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Valneva reports the subjects in Phase II clinical trial of Lyme disease vaccine develop antibodies.  The results were positive enough to inspire Pfizer to join with Valneva to continue testing in the next phase of clinical trials and, hopefully, bring this to market. Find out more about the vaccine strategy and Lyme disease: Read More … Read more

Building Better Antibodies

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Antibodies are proteins. In the body, they are made by B cells of the immune system. To produce antibodies as therapeutics, they are synthesized by cells in culture. The structure of an antibody is defined by the amino acid sequence of the protein (Figure 1). The incredible diversity of antibodies, which is essential to our … Read more

Virally Modified Cells Regenerate Normal Skin

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Stem cells hold great promise for medical intervention. However, it has been difficult to leverage these cells effectively. In the study by Hirsch and colleagues, a collaboration between doctors and researchers saved the life of a child with a skin disorder called junctional epidermolysis bullosa (JEB). JEB is a genetic disease caused by mutations in … Read more

Desert Green Algae and Cyanobacteria for Synthetic Biology

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Synthetic biology is the discipline of designing and then engineering artificial systems using biological components. The field of molecular biology and the ability to read the information encoded in DNA are critical to this technical discipline, which also relies on the principles of engineering, detailed knowledge of cell biology, and an understanding of chemistry. Synthetic … Read more