Intratumor Immunotherapy Kills Injected and Distant Tumors

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Cancerous tumors must evade immune destruction to survive. They can achieve this by preventing the immune cells from gaining access to the tumor (“immune cold”) or by tipping the balance of immunoactivating and immunosuppressing signals toward immunosuppression. Immunosuppression means that, even if the immune cells penetrate the tumor, they cannot kill the cancer. The cytotoxicity … Read moreIntratumor Immunotherapy Kills Injected and Distant Tumors

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Engineering the Immune System to Treat Diabetes

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Some diseases arise because the immune system reacts with normal, healthy cells in the body. In other diseases, lack of an effective immune response contributes to the disease. Cancer cells escape attack by the immune system, in part, by producing a lot of the protein PD-L1 (Gough, 24 May 2017). PD-L1 binds and activates the … Read moreEngineering the Immune System to Treat Diabetes

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Can you be vaccinated against yourself?

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A vaccine may be described as medicine that stimulates an immune response with a “memory.” Many people also consider a vaccine to be a medicine that prevents a disease caused by a pathogen. Indeed, the first vaccines were ones that prevented infectious diseases, such as polio and measles. Some vaccines have been so successful that … Read moreCan you be vaccinated against yourself?

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