Scar-Detecting Nanoparticles

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Scars are the body’s response to skin injury. Sometimes too much of the protein collagen is produced at the site of the injury, resulting in excessively large thick scars that can be disfiguring, uncomfortable, and compromise function by restricting mobility. These can either be hypertrophic scars, which are thickened but limited to the injured area, … Read moreScar-Detecting Nanoparticles

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Blocking Nuclear Translocation to Treat Cancer and Colitis

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Many proteins have multiple roles. Often, the key to effective therapy is specificity. Not only does the treatment need to be specific for a particular physiological target, often a protein, but the therapeutic effects involve only a single function or subset of the target’s functions or needs to affect the target only within a specific … Read moreBlocking Nuclear Translocation to Treat Cancer and Colitis

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Secreted Kinases May Promote Malignancy

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Protein kinases are enzymes that add phosphate groups onto specific amino acids on proteins. Most of these enzymes are active within cells. Kinases are often encoded by oncogenes, and aberrant activity of these regulatory enzymes is frequently associated with cancer. Data are emerging that kinases can also be released from cells. These secreted kinases can … Read moreSecreted Kinases May Promote Malignancy

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