The Power of Proteomics in Medicine

mass_spectrometry_proteomics
Share

  Although genomic (DNA) and transcriptomic (messenger RNA) data are easier to collect and analyze, these are only two of the relevant types of “omic” data that are important for understanding disease and the response to treatments. Proteomic, metabolomic, and lipidomic data are also contain information that can be used diagnostically, prognostically, in developing treatment … Read moreThe Power of Proteomics in Medicine

Share

The Power of Proteomics in Building the Human Protein Interaction Network

CDK4_Interaction_Network
Share

Defining >56,000 Human Protein Interactions through Mass Spectrometry Huttlin and colleagues applied mass spectrometric analysis to affinity purified protein complexes to help build a partial reference map of the human protein interaction space (1). The cDNA encoding the target proteins also engineered to have affinity tags (hemagglutinin and FLAG) were introduced into an easily infected … Read moreThe Power of Proteomics in Building the Human Protein Interaction Network

Share

Proteomics Improves Antigen Prediction

Vaccine_development
Share

How will we benefit from being able to accurately predict the peptide antigens that the immune system can recognize? Vaccine development would be a major beneficiary of such knowledge (Figure 1). We could produce more effective and safer vaccines. We could develop vaccines for pathogens for which no vaccine is currently available. We could ensure … Read moreProteomics Improves Antigen Prediction

Share