GDF15: Heart Hormone, Appetite Suppressant, Marker of Neurodegenerative Disease

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Coordinating growth with heart health ensures that the heart can keep up with the demands placed on it by the body. A recent study (1) identified a molecule called growth differentiation factor 15 [GDF15, also known as macrophage inhibitory cytokine 1 (MIC1)] that was released from the heart that signals to the liver to inhibit … Read more

Bionic Organs with Silicon Nanopore Membranes

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One of the challenges to building artificial organs is finding or creating suitable materials for use in such devices. If the device contains living cells, then those cells need to receive nutrients from, exchange gases with, and send cellular waste products into blood. In addition, the cells should also respond appropriately to circulating regulatory signals, … Read more

Challenges in Classifying Biology

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There are multiple ways to categorize nearly everything in biology. The value of an individual categorization scheme depends on the perspective of the user. As Shirley Malcom (former Director, Education and Human Resources Programs, AAAS) once said, “We [Biologists] are splitters not lumpers.” This need for classification makes consensus difficult, can limit our way of … Read more