Blocking Nuclear Translocation to Treat Cancer and Colitis

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Many proteins have multiple roles. Often, the key to effective therapy is specificity. Not only does the treatment need to be specific for a particular physiological target, often a protein, but the therapeutic effects involve only a single function or subset of the target’s functions or needs to affect the target only within a specific … Read moreBlocking Nuclear Translocation to Treat Cancer and Colitis

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Understanding Immune Checkpoint Pathways to Improve Patient Response

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Better understanding of the molecular mechanisms that control the adaptive immune system will lead to better immunotherapies for cancer patients or patients with other diseases related to inappropriate immune responses. Two of the processes that inhibit T cell function are called immune checkpoint pathways. New research reveals that these pathways involve many cells of the … Read moreUnderstanding Immune Checkpoint Pathways to Improve Patient Response

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