Pancreatic Cancer: A Biomarker Challenge

pancreatic_cancer

Frequently, I am asked, “Isn’t there a blood test for pancreatic cancer?” I think this question arises because, as my friends and I are getting older, we have more friends, relatives, and acquaintances who are diagnosed with cancer, and those with pancreatic cancer are the ones that tend to die soonest. Many have heard of … Read more

Context Matters for Targeting MYC in Cancer

Omomyc_bound_to_DNA

Two studies in March 2019 focus on MYC as a target in cancer. MYC is encoded by a well known oncogene, meaning that it can promote cancer. However, MYC has both pro-cancer and anti-cancer properties. The anti-cancer activity tends to dominate when there is more of this protein in the cell; the pro-cancer activity dominates … Read more

A Closer Look: 10 March 2019

thumbs_up_thumbs_down

A list of articles classified by Nancy R. Gough as good, valuable contributions or not so valuable contributions to the scientific literature.

Gut Microbes in Graft-Versus-Host Disease

shifting_microbiome_balance

Graft-versus-host disease (GVHD) is occurs in people who have received bone marrow or blood stem cell transplants from donors (allogenic transplants). The donated cells replace the stem cells that make the cells of the immune system and red blood cells in patients with leukemias or lymphomas or various types of bone marrow diseases, blood disorders, … Read more