Context Matters for Targeting MYC in Cancer

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Two studies in March 2019 focus on MYC as a target in cancer. MYC is encoded by a well known oncogene, meaning that it can promote cancer. However, MYC has both pro-cancer and anti-cancer properties. The anti-cancer activity tends to dominate when there is more of this protein in the cell; the pro-cancer activity dominates … Read more

Single-Cell Proteomics Shines Light on the Complexity of Immune Cells in Solid Tumors

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A Proteomic Approach to the Tumor Microenvironment An outstanding issue in treating solid cancers is understanding the complexity of this pathological tissue. Solid tumors are comprised not only of the cancer cells, but they also contain immune cells, cells that form blood vessels and lymphatic vessels, fibroblasts, and the stem cells that form the fibroblasts … Read more