Discovering Fast-Acting Treatments for Depression

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Depression is a complex and common disease. In the US, 1 in 6 people will experience clinical depression sometime in his or her life. There are likely multiple underlying cellular or molecular causes of clinical depression. This is why not all patients respond to any given therapy. Symptoms of clinical depression are diverse and sometimes contradictory. … Read more

Giving Mice Artificial Memories to Discover Clues to Depression

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Changes in how the brain processes memories of pleasurable or rewarding experiences contribute to addiction and depression. A study in mice by LeGates and colleagues provides clues to how the brain processes and remembers rewards, which is key to understanding and treating these mental health disorders. They used light-activated proteins (optogenetics) to alter the strength … Read more