In the center is the structure of the antibody IgG from PDB: 1IGT. One the left side is an antibody with glycosylation patterns that tend to cause allergic reactions. On the right is an antibody with customized glycosylation patterns that eliminate the antigenic sugars and include modifications that enhance immune cell receptor binding. The antibody structure is from PDB:1IGT. Read more:
N. R. Gough, Building Better Antibodies. BioSerendipity (6 November 2018) https://www.bioserendipity.com/building-better-antibodies/.