Studies in mice show that peptides that block the nuclear import of specific proteins are a therapeutic strategy to prevent colitis and inflammation-associated colon cancer. The healthy colon image is from NIH. The figure is compiled by Nancy R. Gough, BioSerendipity.
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N. R. Gough, Blocking Nuclear Translocation to Treat Cancer and Colitis. BioSerendipity (16 April 2018) www.bioserendipity.com/blocking-nuclear-translocation-to-treat-cancer-and-colitis.